Available Videos, Lectures and Podcasts
Online Videos Featuring our Lab and Technology From the Lab
Mike Roberts’ Presentation at NVIDIA Research Conference
Research from Mike Roberts and Jeff Packer has been featured on Nvidia Corporation’s website. The research describes a new massively parallel algorithm that will improve treatment planning and assessment by allowing physicians to quickly, accurately, and reliably identify and measure objects in 3D medical images. The new algorithm is 14x faster than previous algorithms without affecting accuracy.
- 19th May 2010 – Thorarin A Bjarnason. Quantitative T2: Software, Application, Workflows, Phase Correction – April 2010. This podcast was recorded during Thorarin Bjarnason’s PhD public defense lecture. Quantitative T2 (qT2) is an emerging MRI field that utilizes the fundamental MRI T2 relaxation process and shows promise of being a non-invasive biomarker for myelin health. This thesis addresses a few limitations of qT2 understanding and analysis, including both a thorough examination of qT2 attributes that characterize more than just myelin health and improved methods of analysis. To begin, a thorough introduction of qT2 in terms of acquisition and analysis is presented, followed by a review of applications. Four studies of qT2 follow. The first study addresses qT2 analysis, presenting an open source, platform independent qT2 software package that works with data independent of MR manufacturer. A histology study follows. The next study addresses the optimal qT2 analysis method. Finally, noise is examined. Quantitative T2 analysis is best performed on data with Gaussian distributed noise, but MRI noise is Rician distributed and simulations show that Rician noise affects the T2 distribution. A temporal phase correction method is developed and applied to in vivo human and rat qT2 data to change the noise from Rician to Gaussian prior to performing qT2 analysis.
Format Size 42MB (19 mins long)
- 15th Dec 2009 – Thorarin A Bjarnason, Tonima Ali, Mark Simpson, Cornelia Laule, J Ross Mitchell. Quantitative T2 (qT2): more than just a shade of grey – October 2009. T2 is commonly associated with different contrasts in MRI, which allows white and grey matter in brain to be visually separable as different shades of grey. By understanding the physics behind T2 we can use this relaxation mechanism to better characterize water within tissue. In this lecture I will briefly review the physics of T2 in order to highlight how it can be used as a contrast mechanism in MRI. A description of quantitative T2 (qT2) naturally follows, introducing the T2 distribution, which is a way of fully representing T2 relaxation times within an MR image. qT2 literature is reviewed, showing how different aspects of the T2 distribution reflect biology. For instance, short T2 times in the T2 distribution has been shown to correlate with myelin content, which could prove invaluable in monitoring neurodegenerative diseases such as multiple sclerosis (MS). Additionally, long T2 times in the T2 distribution highlights active lesions in MS patients. By fully characterizing the T2 relaxation process using MRI, T2 can be more than just a shade of grey.
Format Size 118MB (40 mins long)
- 14th May 2009 – Thorarin A Bjarnason, Tonima Ali, Mark Simpson, J Ross Mitchell, Cornelia Laule.Quantitative T2 with Application in Brain Cancer – March 2009. An introduction to MRI quantitative T2 (qT2) is presented along with applications to brain cancer. We begin by describing how MRI can be sensitive different water environments within a single pixel. We review histopathological validation of qT2 for measuring myelin and present recent findings of newly discovered water environments in various brain diseases. We finish off the presentation highlighting recent applications of qT2 in cancer and discuss our recent findings and research directions.
Format Size 59MB (26 mins long) 197MB
- 18th December 2008 – Thorarin A B jarnason, J Ross Mitchell. How to use AnalyzeNNLS – December 2008. This video podcast outlines how to use AnalyzeNNLS, an opensource project from ImagingInformatics.ca. AnalyzeNNLS is designed to analyze mulicompartment T2 decays from multiecho MRI experiments. This podcast provides a tutorial on how to use AnalyzeNNLS to analyze single-slice and multi-slice multiecho data.
Format Size 50MB (11 mins long) 177MB
- 20th November 2008 – Thorarin A Bjarnason, Tonima Ali, Mark Simpson, J Ross Mitchell. Quantitative T2: Software, Workflow, Phase Correction – November 2008. This video podcast outlines 3 main areas of Thorarin Bjarnason’s PhD research to improve quantitative T2 (qT2). 1) Software: Opensource qT2 analysis software is described. More recently, we have been developing a qT2 visualization tool. 2) Workflows: Different workflows have been studied for qT2 analysis and we found that non-regularized multivoxel analysis is best suited for qT2. 3) Phase Correction: Phase correcting multiecho data changes the noise-type from Rician to Gaussian. Gaussian noise is preferred for qT2 analysis algorithms.
Format Size 67MB (29 mins long) 186MB
- 29th October 2008 – Thorarin A Bjarnason, Sylvia Drabycz, Mark Simpson, Ming Zhang, Tonima Ali, Mike Roberts, J Ross Mitchell. Medical Imaging Informatics – Towards Virtual Biopsy – October 2008.
Thor presented this talk at the Welcome to New Students Seminar in . In this presentation we provide an introduction to Medical Imaging Informatics and the current research of ImagingInformatics.ca. We outline 3D visualization and tissue characterization and the roles they are playing in virtual biopsy of brain cancer tumors.
|54MB (22 mins long)|
- 14th July 2008 – Thorarin A Bjarnason, Cheryl R McCreary, Jeff F Dunn, J Ross Mitchell. Comparing Multiecho Analysis Workflows. Thor presented this talk at the Advanced Imaging Seminar Series. In this research a few multiecho analysis methods are compared and a voxel based, non regulariazed approach is recommended for multiecho T2 analysis.
Format Size 10MB (18 mins long) 18MB
- 1st November 2007 – Mark Simpson presented the iiDicom Framework for Objective C and Python complete with code demonstrations. The podcast here is presented in two versions (hi-res provides better code clarity on screen)
Format Size 61.1MB (25 mins long) 427.3MB (hi-res)
- 9th March 2007 – Thorarin A Bjarnason, Cornelia Laule, J Ross Mitchell. Myelin Water Imaging and Histopathology. Thor lead a discussion of a recent article on myelin water imaging in the MS Journal Club at the University of Calgary. Article: Article: Laule C, Leung E, Li DKB, Traboulsee AL, Paty DW, MacKay AL, Moore GRW. “Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology.” Multiple Sclerosis; 12:747-53 (2006).
|46.6MB (32 mins long)|
- 6th January 2007 – Thorarin Bjarnason presented his research at the Advanced Imaging Seminar Series. This work outlines the use of phase correction on multiecho MR images in order to change the noise distribution from Rician to Gaussian-like. His results show the loss of the commonly labeled cerebral spinal fluid peak from the T2 distribution.
|22.3MB (20 mins long)|
- 13th December 2006 – Dr Mitchell presented an overview of time/frequency analysis in medical imaging of stroke, brain cancer, multiple sclerosis, and epilepsy at the ISAAC Workshop on Pseudo-Differential Operators: Partial Differential Equations and Time-Frequency Analysis at the Fields Institute. The extension of these techniques to seismology are shown.
|77.2MB (44 mins long)|
- 26th May 2006 – Dr Michael D Hill, from the Calgary Stroke Program, gives a podcast entitled “ “. We have also made a copy of his slides available. They are in a movie. To advance these slides view them using the Quicktime player, then simply click in the slide movie window. This will allow you to follow along, but view a higher quality version of Dr. Hill’s slides, as he gives his lecture.
|193MB (32 mins long)|
|Slides||2.7 MB (40 slides)|
- 28th March 2006 – Dr Mitchell presented a lecture on time/frequency analysis of medical images for the PIMS/Shell Lunchbox Lecture Series.